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polyclonal rabbit anti human leptin ab  (BioVendor Instruments)


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    BioVendor Instruments polyclonal rabbit anti human leptin ab
    <t>Leptin</t> depletion or neutralization inhibits <t>polyclonal</t> T cell proliferation and mixed lymphocyte reactions (MLR), respectively. (a–c)The proliferative response of T lymphocytes to polyclonal stimuli (OKT3, PHA, and PMA/Iono) from controls is completely inhibited in medium with human serum depleted of leptin. Addition of recombinant human leptin (at 100 ng/ml final concentration) completely reverses this phenomenon. (d) Anti-leptin blocking Abs partially inhibit the antigen-specific proliferative response of T cells during MLR. HS, human serum.
    Polyclonal Rabbit Anti Human Leptin Ab, supplied by BioVendor Instruments, used in various techniques. Bioz Stars score: 92/100, based on 8 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/polyclonal+rabbit+anti+human+leptin+ab/pmc01482518-251-21-26?v=BioVendor+Instruments
    Average 92 stars, based on 8 article reviews
    polyclonal rabbit anti human leptin ab - by Bioz Stars, 2026-07
    92/100 stars

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    1) Product Images from "Differential regulation of metabolic, neuroendocrine, and immune function by leptin in humans"

    Article Title: Differential regulation of metabolic, neuroendocrine, and immune function by leptin in humans

    Journal:

    doi: 10.1073/pnas.0505429103

    Leptin depletion or neutralization inhibits polyclonal T cell proliferation and mixed lymphocyte reactions (MLR), respectively. (a–c)The proliferative response of T lymphocytes to polyclonal stimuli (OKT3, PHA, and PMA/Iono) from controls is completely inhibited in medium with human serum depleted of leptin. Addition of recombinant human leptin (at 100 ng/ml final concentration) completely reverses this phenomenon. (d) Anti-leptin blocking Abs partially inhibit the antigen-specific proliferative response of T cells during MLR. HS, human serum.
    Figure Legend Snippet: Leptin depletion or neutralization inhibits polyclonal T cell proliferation and mixed lymphocyte reactions (MLR), respectively. (a–c)The proliferative response of T lymphocytes to polyclonal stimuli (OKT3, PHA, and PMA/Iono) from controls is completely inhibited in medium with human serum depleted of leptin. Addition of recombinant human leptin (at 100 ng/ml final concentration) completely reverses this phenomenon. (d) Anti-leptin blocking Abs partially inhibit the antigen-specific proliferative response of T cells during MLR. HS, human serum.

    Techniques Used: Neutralization, Recombinant, Concentration Assay, Blocking Assay



    Similar Products

    rabbit polyclonal ab against human leptin  (Santa Cruz Biotechnology)
    95
    Santa Cruz Biotechnology rabbit polyclonal ab against human leptin
    FIGURE 1. Immunohistochemical detection of lep- tin protein in BECs, pneumocytes, alveolar macro- phages, and smooth muscle cells of the airways and pulmonary vessels in (CS-exposed) WT mice. C57BL/ 6 WT mice were exposed to air or CS for 4 or 24 wk, and <t>leptin</t> protein was detected by immunohistochem- ical staining. A, Air-exposed WT mice at 4 wk. B, CS- exposed WT mice at 4 wk. C, Air-exposed WT mice at 24 wk. D, CS-exposed WT mice at 24 wk. Photomicro- graphs (magnification 3200) are representative of eight animals per group. E, Quantification of leptin-positive BECs. Results are expressed as percentage leptin- positive BECs of total counted BECs (mean 6 SEM, n = 8 animals per group; pp , 0.05). F, Quantification of leptin-positive pneumocytes. Results represent semi- quantitative scoring by two independent observers on a five-point scale (mean 6 SEM, n = 8 animals per group; pp , 0.05).
    Rabbit Polyclonal Ab Against Human Leptin, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/polyclonal+rabbit+anti+human+leptin+ab/pm20488786-79-5-12?v=Santa+Cruz+Biotechnology
    Average 95 stars, based on 1 article reviews
    rabbit polyclonal ab against human leptin - by Bioz Stars, 2026-07
    95/100 stars
    		  Buy from Supplier
    polyclonal rabbit anti human leptin ab  (BioVendor Instruments)
    92
    BioVendor Instruments polyclonal rabbit anti human leptin ab
    <t>Leptin</t> depletion or neutralization inhibits <t>polyclonal</t> T cell proliferation and mixed lymphocyte reactions (MLR), respectively. (a–c)The proliferative response of T lymphocytes to polyclonal stimuli (OKT3, PHA, and PMA/Iono) from controls is completely inhibited in medium with human serum depleted of leptin. Addition of recombinant human leptin (at 100 ng/ml final concentration) completely reverses this phenomenon. (d) Anti-leptin blocking Abs partially inhibit the antigen-specific proliferative response of T cells during MLR. HS, human serum.
    Polyclonal Rabbit Anti Human Leptin Ab, supplied by BioVendor Instruments, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/polyclonal+rabbit+anti+human+leptin+ab/pmc01482518-251-21-26?v=BioVendor+Instruments
    Average 92 stars, based on 1 article reviews
    polyclonal rabbit anti human leptin ab - by Bioz Stars, 2026-07
    92/100 stars
    		  Buy from Supplier

    Image Search Results


    FIGURE 1. Immunohistochemical detection of lep- tin protein in BECs, pneumocytes, alveolar macro- phages, and smooth muscle cells of the airways and pulmonary vessels in (CS-exposed) WT mice. C57BL/ 6 WT mice were exposed to air or CS for 4 or 24 wk, and leptin protein was detected by immunohistochem- ical staining. A, Air-exposed WT mice at 4 wk. B, CS- exposed WT mice at 4 wk. C, Air-exposed WT mice at 24 wk. D, CS-exposed WT mice at 24 wk. Photomicro- graphs (magnification 3200) are representative of eight animals per group. E, Quantification of leptin-positive BECs. Results are expressed as percentage leptin- positive BECs of total counted BECs (mean 6 SEM, n = 8 animals per group; pp , 0.05). F, Quantification of leptin-positive pneumocytes. Results represent semi- quantitative scoring by two independent observers on a five-point scale (mean 6 SEM, n = 8 animals per group; pp , 0.05).

    Journal: Journal of immunology (Baltimore, Md. : 1950)

    Article Title: Leptin modulates innate and adaptive immune cell recruitment after cigarette smoke exposure in mice.

    doi: 10.4049/jimmunol.0900963

    Figure Lengend Snippet: FIGURE 1. Immunohistochemical detection of lep- tin protein in BECs, pneumocytes, alveolar macro- phages, and smooth muscle cells of the airways and pulmonary vessels in (CS-exposed) WT mice. C57BL/ 6 WT mice were exposed to air or CS for 4 or 24 wk, and leptin protein was detected by immunohistochem- ical staining. A, Air-exposed WT mice at 4 wk. B, CS- exposed WT mice at 4 wk. C, Air-exposed WT mice at 24 wk. D, CS-exposed WT mice at 24 wk. Photomicro- graphs (magnification 3200) are representative of eight animals per group. E, Quantification of leptin-positive BECs. Results are expressed as percentage leptin- positive BECs of total counted BECs (mean 6 SEM, n = 8 animals per group; pp , 0.05). F, Quantification of leptin-positive pneumocytes. Results represent semi- quantitative scoring by two independent observers on a five-point scale (mean 6 SEM, n = 8 animals per group; pp , 0.05).

    Article Snippet: Leptin was detected using a rabbit polyclonal Ab against human leptin (SC-842, Santa Cruz Biotechnology, Santa Cruz, CA), which crossreacts with mouse leptin.

    Techniques: Immunohistochemical staining, Staining

    Leptin depletion or neutralization inhibits polyclonal T cell proliferation and mixed lymphocyte reactions (MLR), respectively. (a–c)The proliferative response of T lymphocytes to polyclonal stimuli (OKT3, PHA, and PMA/Iono) from controls is completely inhibited in medium with human serum depleted of leptin. Addition of recombinant human leptin (at 100 ng/ml final concentration) completely reverses this phenomenon. (d) Anti-leptin blocking Abs partially inhibit the antigen-specific proliferative response of T cells during MLR. HS, human serum.

    Journal:

    Article Title: Differential regulation of metabolic, neuroendocrine, and immune function by leptin in humans

    doi: 10.1073/pnas.0505429103

    Figure Lengend Snippet: Leptin depletion or neutralization inhibits polyclonal T cell proliferation and mixed lymphocyte reactions (MLR), respectively. (a–c)The proliferative response of T lymphocytes to polyclonal stimuli (OKT3, PHA, and PMA/Iono) from controls is completely inhibited in medium with human serum depleted of leptin. Addition of recombinant human leptin (at 100 ng/ml final concentration) completely reverses this phenomenon. (d) Anti-leptin blocking Abs partially inhibit the antigen-specific proliferative response of T cells during MLR. HS, human serum.

    Article Snippet: For leptin depletion from serum, a protein G-Sepharose affinity column (Amersham Pharmacia) was used after adhesion on G protein of a polyclonal rabbit anti-human leptin Ab (BioVendor).

    Techniques: Neutralization, Recombinant, Concentration Assay, Blocking Assay